Malignant transformation of hymenolepis nana in a human. Praziquantel, adults and children, 25mgkg in a singledose therapy alternatives. The fine structure of the envelopes surrounding hatched and unhatched oncospheres of hymenolepis nana has been investigated by transmission and scanning electron microscopy sem, together with light microscope histochemical observations of jb4 embedded material. Hymenolepis nana infection of the colon in an adult male. See more ideas about medical laboratory, microbiology and medical laboratory science. It is endemic in asia, southern and eastern europe, central and south america, and africa, and produces many health problems such as headaches, weakness, anorexia, abdominal pain. It once held two other scientific names including vampirolepis nana and taenia nana 4. Nov 22, 2015 hymenolepiasis is the term when a human is infected with either h.
The infection is more frequently seen in children although adults are also infected. Hymenolepis nanainfected children present at medical facilities with restlessness, irritability, diarrhoea, abdominal pain, pruritus ani or nasal pruritus despite clear symptomatology in case series romerocabello et al. This infection does not require an intermediate host and infection can occur directly from one. Hymenolepis nana is an exception among the cestodes, as it can develop directly in the. This cestode belongs to a large family known as hymenolepididae. All structured data from the file and property namespaces is available under the creative commons cc0 license. Whether its customized environmental isolate controls, process controls, certified reference materials, proficiency samples, or something thats never been done before were up to the challenge. The fine structure of the envelopes surrounding hatched and unhatched oncospheres of hymenolepis nana has been investigated by transmission and scanning electron microscopy sem, together with light microscope histochemical observations of jb4. Hymenolepis nana dwarf tapeworm parasites in humans. The most characteristic feature in this worm is its eggs, with a higher. The fact that an intermediate host is not required in the life cycle was determined in the late 1800s. Pdf hymenolepis nana human diagnosed through colonoscopy.
The dwarf tapeworm was found in man for the first time by bilharz, in cairo, egypt, in 1851. Malignant transformation of hymenolepis nana in a human host to the editor. This infection does not require an intermediate host and infection can occur directly from one infected person to another by fecaloral transmission. Hymenolepis diminuta infection infectious diseases msd. Dr kishor ingole, dr mayuri bhise, dr bhakti chiluvery, dr anu sharma. Apr 20, 2015 hymenolepiasis is the most common intestinal tapeworm infection of humans caused by worm of family cestoda, genus hymenolepis and species nana. Later, morphological characteristics were used for taxonomy identification and h.
The medullary region of the gravid proglottid is entirely occupied by a sacculate uterus containing up. She remained well in spite of treatment, even though. The scolex of hymenolepis nana shows suckers and an invaginated rostellum. We therefore diagnosed hymenolepis nana internal autoinfection involving the total colon in an asymptomatic adult. What is hymenolepis nana infection the dwarf tapeworm or hymenolepis nana is found worldwide. Eggs hatch in the duodenum, releasing oncospheres, which penetrate the mucosa and come to lie in lymph channels of the villi. Media in category hymenolepis nana the following 7 files are in this category, out of 7 total. Some common intermediate hosts include flour moths, flour beetles, meal worms, and cockroaches. Hymenolepis nana pathogen intestinal cestode organism. Files are available under licenses specified on their description page. Cdc hymenolepis resources for health professionals. It is the first known case of a person becoming ill from cancer cells that arose in a parasite in this case, hymenolepis nana, the dwarf tapeworm.
Hymenolepis nana infection did not have a significant impact on clinical symptoms in this community. Human infection is usually asymptomatic, it but can cause mild gastrointestinal symptoms. Hymenolepis nana dwarf tapeworm infection infectious. Development hymenolepis nana life cycle infection is acquired most commonly from eggs in the feces of another infected individual, which are transferred in food, by contamination. It requires only one host but can also cycle through two. Hymenolepis nana introduction hymenolepis nana, the dwarf tapeworm, is the smallest tapeworm to infect humans. Midle part of gravid proglottids, acetocarmine stain, x450. We thrive on creating innovative biological reference materials that make microbiologists lives easier.
Hymenolepis diminuta is a tapeworm that can cause intestinal infection in humans. The oncosphere is surrounded by 3 layers the capsule, the outer envelope and the inner envelope, the latter giving rise. Here, we present a case of a renal transplant recipient who presented with abdominal pain and developed diarrhea. Scolex of hymenolepis nana showing 2 suckers and rostellum with hooksa. Areas of endemicity up to 26% prevalence include asia, southern and eastern europe. Selfing appears to increase the frequency of cysticercoid abnormalities. The outside shell is translucent, elastic, cracking in sharp angles under pressure, and only 0. During the course of a survey on the intestinal protozoan infections among 362 children in st. Hymenolepiasis is caused by two cestodes tapeworm species, hymenolepis nana the dwarf tapeworm, adults measuring 15 to 40 mm in length and hymenolepis diminuta rat tapeworm, adults measuring 20 to 60 cm in length. On the inner membrane are two poles, from which 4 to 8 polar filaments spread out between the two membranes. Hymenolepis nana has been called the dwarf tapeworm and has a worldwide distribution. Hymenolepis nana definition of hymenolepis nana by medical. He recovered a countless number of them at a postmortem on a boy who had died of meningitis.
Infection is most common in children, in persons living in institutional settings, and in people who live in areas where sanitation and personal hygiene is inadequate. Hymenolepiasis is the term when a human is infected with either h. Hymenolepis nana bilharz, 1851 ransom, 1901 1 dwarf tapeworm hymenolepis nana, also known as rodentolepis nana, vampirolepis nana, hymenolepis fraterna, and taenia nana is a cosmopolitan species though most common in temperate zones, and is one of the most common cestodes a type of intestinal worm or helminth infecting humans. Himenolepiasis parasitologia humana accessmedicina. Malignant transformation of hymenolepis nana in a human host article pdf available in new england journal of medicine 37319.
The majority of helminth parasites that are considered by who to be the cause of neglected diseases are zoonotic. The oncosphere is surrounded by 3 layers the capsule, the outer envelope and. Hymenolepis nana article about hymenolepis nana by the free. Effects of continued selfing on hymenolepis nano cestoda. The proportion of eggs developing into cysticercoids in tribolium confusum appears to decrease with continued selfing. The authors cite some ear lier cases as examples of proliferating. Humans, rodents most common tapeworm of humans in the world 1% rate of infection in the southern u. Hymenolepis diminuta is a cestode of rodents infrequently seen in humans and frequently found in rodents. In 1906, stiles identified an identical parasite with a rodent host and named it hymenolepis fraterna. Pdf malignant transformation of hymenolepis nana in a human. All structured data from the file and property namespaces is available under the. Although abdominal pain was highly prevalent, as previously reported romerocabello et al. Hymenolepis nana, the dwarf or dwarf mouse tapeworm, is a small tapeworm in humans, sometimes found in great numbers in the intestine.
The most characteristic feature in this worm is its eggs, with a higher power, we easily distinguish three distinct eggshells fig. Hymenolepis nana, the dwarf tapeworm, is the smallest tapeworm to infect humans. The effects of selfing on hymenolepis nana were investigated by establishing single infections in mice, thus ensuring selffertilization. Hymenolepiasis is the most common intestinal tapeworm infection of humans caused by worm of family cestoda, genus hymenolepis and species nana. Click the button below to download a pdf of our latest catalog. Similarly, the proportion of cysticercoids developing into adults. It is inside the body cavity of these intermediate hosts that the ingested egg by way of contaminated feces hatches and. It is also known as the dwarf tapeworm due to its particularly small size adults are only 1540 mm long. It is primarily tapeworm and humans usually children can act as accidental hosts.
Rodents are the primary definitive hosts, and grain beetles, fleas, or other insects feed on contaminated rodent droppings as intermediate. One reason for facultative nature of the lifecycle is that h. Drugs used to treat dwarf tapeworm infection hymenolepis nana the following list of medications are in some way related to, or used in the treatment of this. A taxonomic genus within the family hymenolepididae tapeworms responsible for hymenolepiasis. This page was last edited on 7 january 2016, at 10. Hymenolepis nana article about hymenolepis nana by the. Genebased molecular characterization of cox1 and pnad5 in. Hymenolepis nana, typically a parasite found in conventionally established mouse colonies, has zoonotic potential characterized by auto infection and. Pdf hymenolepis nana infestation is commonly diagnosed in schoolaged children and very rarely.
Tsuchiya, three cases of infection with hymenolepis nana were incidentally encountered. Its larvae migrate only within the gut wall, and its life span is relatively short 4 to 6 wk. Hymenolepiasis a helminthic disease of man, mammals, and some birds. It is small and measures up to 2540 mm in length by one mm in diameter. Pdf malignant transformation of hymenolepis nana in a. Hymenolepis nana, a tiny intestinal tapeworm, is the most common human cestode.
Larval and adult beetles but optional larval stage, cysticercoid, can develop. It has a cosmopolitan distribution and is thought to be the most common tapeworm throughout the world. Introduction the dwarf tapeworm is a species of tapeworm that is classified in the platyhelminthes phylum. Hymenolepis nana vs hymenolepis dimunota medical laboratories.
Larval and adult beetles but optional larval stage, cysticercoid, can develop in d. Hymenolepis nana, also known as dwarf tapeworm, is a cyclophyllidean tapeworm with embryonated eggs. Hymenolepis nana is the most common tapeworm in humans. The dwarf tapeworm, hymenolepis nana, cancer cells linked to. Hymenolepis nana definition of hymenolepis nana by. Pdf heavy hymenolepis nana infection possibly through organic. Hymenolepis nana has a worldwide distribution with estimates of 5075 million carriers. Diplacanthus manus, hymenolepis nana, hymenolepis murina. Hymenolepis nana is the most prevalent humaninfecting tapeworm worldwide and in peruvian communities.
In this article we will discuss about hymenolepis nana. Hymenolepis nana, a common tapeworm that is distributed worldwide, is found mostly in young children in developing countries. Malignant transformation of hymenolepis nana in a human host. If larvabearing eggs enter the human gastrointestinal tract, the oncospheres are released into the duodenum and attatch to the villi, where each develops into a cysticercoid. In man, hymenolepiasis generally results from infection by the dwarf tapeworm, occasionally by the rat tapeworm. The dwarf tapeworm, hymenolepis nana, cancer cells linked. Dwarf tapeworm hymenolepis nana, previously known as vampirolepis nana, hymenolepis fraterna, and taenia nana is a cosmopolitan species though most common in temperate zones, and is one of the most common cestodes of humans, especially children. Dwarf tapeworm is a cosmopolitan species though most common in temperate zones, and is. Hymenolepis nana is an intestinal cestode causing tapeworm infection in humans with a worldwide distribution.
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